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Search Results for " 5 alpha Reductase "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T0488	Finasteride	MK-906	Reductase
	Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.		Reductase
T1499	Dutasteride	GG 745,Avodart,GI 198745	Apoptosis , Reductase
	Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.		Apoptosis , Reductase
T71703L	Isomer-Turosteride	Isomer-Turosteride(Isomer-137099-09-3)	Reductase
	Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) is a novel 5 alpha-reductase inhibitor.The antiprostatic effect of Isomer-Turosteride in adult rats is associated with the inhibition of the conversion of T to ...		Reductase
T28249	Ono-3805 sodium	Ono3805,Ono 3805,Ono-3805
	Ono-3805 is an inhibitor of nonsteroidal 5 alpha-reductase.
T70343	FK-143
	FK-143 is a 5-alpha reductase inhibitor.
T70449	Fce 28260
	Fce 28260 is a 5 alpha-reductase inhibitor.
T68757	RMI-18341
	RMI-18341 is a Testosterone 5 alpha reductase inhibitor.
T70448	FCE-27837
	FCE-27837 is a 5-alpha reductase inhibitor and hormone antagonist.
T70438	FCE-28175
	FCE-28175 is a 5-alpha reductase inhibitor and hormone antagonist.
T10179	5β-Dutasteride		Others
	5β-Dutasteride is the S configuration of Dutasteride. It is a potent inhibitor of both 5 alpha-reductase isozymes.		Others
T10780	CGP-53153		Others
			Others
T19574	TBHBA	2,4,6-Tribromo-3-hydroxybenzoic acid	Others
	TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a brominated aromatic compound. It has been found to inhibit the enzyme cyclooxygenase-2 (COX-2), the enzyme lipoxygenase (LOX), the enzyme 5-lipoxygenase (5-LOX), the enzy...		Others

Compounds

Synonym: GG 745,Avodart,GI 198745

Target: Apoptosis, Reductase

Isomer-Turosteride

T71703L

Synonym: Isomer-Turosteride(Isomer-137099-09-3)

Target: Reductase

Ono-3805 sodium

T28249

Synonym: Ono3805,Ono 3805,Ono-3805

Synonym: 2,4,6-Tribromo-3-hydroxybenzoic acid

Target: Others

カタログ番号	製品名	別名	ターゲット
TN2601	12-O-Methylcarnosic acid		Reductase
	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity...		Reductase
T3378	Alpha-Estradiol	Alfatradiol,17α-Estradiol,Epiestrol,Epiestradiol	Estrogen/progestogen Receptor , Reductase , Endogenous Metabolite
	Alpha-Estradiol (Epiestradiol) is an estrogen that inhibits 5alpha-reductase and has potential in the study of androgenetic alopecia.
TN5153	Torilin		MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK
	Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi...

天然物製品

12-O-Methylcarnosic acid

Synonym: Alfatradiol,17α-Estradiol,Epiestrol,Epiestradiol

Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite

Torilin

TN5153

Synonym:

Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00962	AKR1C3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate...
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His)	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His)	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...